Bladder and Renal Cancers: New Insights

iStock 000001697512MediumOur team of urologists recently returned from the 2017 American Urological Association conference in Boston. As part of the event, Dr. Badrinath Konety, Director of the Institute for Prostate and Urologic Cancers, discussed the most influential renal and bladder cancer papers published in the in Journal of Urology in 2016. Here are some of the interesting developments and findings described in these papers. 

  • Researchers found that kidney cancer and bladder cancer patients with severely-low muscle mass (called sarcopenia) have worse long-term survival outcomes following surgery than similar patients with normal muscle mass.1-3

  • Researchers studying bladder cancer mortality trends in the United States, starting in the mid-20th century, found that smoking, well-water use, air pollution and unemployment were risks factors for bladder cancer death.4

  • Patients reporting poorer mental health prior to radical cystectomy surgery for bladder cancer had higher rates of severe complications.5

  • Urologists from multiple institutions collaborated to develop and test a standard checklist for surgeons performing transurethral resection of bladder tumours (TURBT). Their goal was to define, measure and improve the quality of TURBT procedures.6

  • The research findings listed above are not conclusive, but rather provide insights that require further investigation – food for thought for our team. Attending international conferences is one of many ways our urologists keep abreast of the latest research and best practices in urological care, so they’re able to pass this expertise on to patients.
  1. Psutka SP et al. Decreased skeletal muscle mass is associated with an increased risk of mortality after radical nephrectomy for localized renal cell cancer. J Urol. 2016 Feb;195(2):270-6. doi: 10.1016/j.juro.2015.08.072. Epub 2015 Aug 18.

  2. Psutka SP et al. Sarcopenia in patients with bladder cancer undergoing radical cystectomy: impact on cancer-specific and all-cause mortality. Cancer. 2014 Sep 15;120(18):2910-8. doi: 10.1002/cncr.28798. Epub 2014 May 19.

  3. Fukushima H et al. Prognostic significance of sarcopenia in patients with metatastic renal cell carcinoma. J Urol. 2016 Jan;195(1):26-32. doi: 10.1016/j.juro.2015.08.071. Epub 2015 Aug 17.

  4. Smith ND et al. Bladder cancer mortality in the United States: a geographic and temporal analysis of socioeconomic and environmental factors. J Urol. 2016 Feb;195(2):290-6. doi: 10.1016/j.juro.2015.07.091. Epub 2015 Jul 30.

  5. Sharma P et al. Preoperative patient reported mental health is associated with high grade complications after radical cystectomy. J Urol. 2016 Jan;195(1):47-52. doi: 10.1016/j.juro.2015.07.095. Epub 2015 Jul 31.

  6. Anderson C et al. A 10-item checklist improves reporting of critical procedural elements during transurethral resection of bladder tumor. J Urol. 2016 Oct;196(4):1014-20. doi: 10.1016/j.juro.2016.03.151. Epub 2016 Apr 1.
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