Notable urology research in 2018
2018 has been a great year for research in the field of urology. We’ve summarized a selection of the most interesting studies of the year.
Testicular cancer treatment and its effects on sexual functionA team of Danish researchers conducted a study1 of 2,260 long-term survivors of testicular cancer, to estimate the effect of testicular cancer treatment on sexual function. They found that the risk of erectile dysfunction was increased in all treatment groups compared to those patients who only underwent orchiectomy (removal of one or both testicles).
Prostate cancer information on the internetLed by Dr. Kevin Kobes from the University of British Columbia, a team of researchers studied the quality of information on websites accessed by patients with prostate cancer2. The researchers searched “prostate cancer” in Google and reviewed the top 100 hits. Ninety percent of the sites provided information on detection and treatment of prostate cancer, but only 14% of the sites included information on prognosis. The researchers concluded that “reliability of websites presenting prostate cancer information is questionable”.
Another study3, led by researchers at NYU School of Medicine, analyzed the 150 most-viewed YouTube videos on prostate cancer. They found that 75% of the videos described the benefits of various prostate cancer treatment options, while only 53% sufficiently explained risks and side effects of treatment. Another 19% recommended alternative or complimentary therapies that are largely unproven and could be harmful. The researchers concluded that “many popular YouTube videos about prostate cancer contained biased or poor-quality information”.
Kidney stones and menopauseDr. Megan Prochaska and her colleagues examined menopause and the risk of developing kidney stones4. Using data from the Nurses’ Health Study II, the researchers analyzed data from 108,639 participants who provided information on menopause and kidney stones. In addition, they analyzed urine tests from 658 participants who collected their urine while premenopausal and then again after menopause. Results showed that postmenopausal women had a higher risk of developing kidney stones.
Drinking more water prevents urinary tract infectionsAn international team of researchers tested the theory that increased water intake helps to prevent recurring urinary tract infections (UTIs)5. They studied 143 healthy women who had a history of recurrent UTIs. Half of the women were assigned to drink an additional 1.5 litres of water per day, the other half of the women were to continue their normal practice of water intake. Results showed that the group of women who drank extra water had approximately half the number of UTIs over one year as the control group.
Diet affects male fertilityDr. Feiby Nassan and her colleagues reviewed the current research on how diet affects male fertility6. They focused on the dietary factors needed for production of healthy sperm. Results showed that eating seafood, poultry, nuts, whole grains, fruits and vegetables is favourable to producing healthy sperm. Also, research supports the use of antioxidant supplements and increasing intake of omega-3 fatty acids from fish and nuts to improve male fertility.
- Bandak M, Lauritsen J, Johansen C, Kreiberg M, Skøtt JW, Agerbaek M, Holm NV, Daugaard G. Sexual Function in a Nationwide Cohort of 2,260 Survivors of Testicular Cancer after 17 Years of Followup. J Urol. 2018 Oct;200(4):794-800.
- Kobes K, Harris IB, Regehr G, Tekian A, Ingledew PA. Malignant websites? Analyzing the quality of prostate cancer education web resources. Can Urol Assoc J. 2018 Oct;12(10):344-350.
- Loeb S, Sengupta S, Butaney M, Macaluso JN Jr, Czarniecki SW, Robbins R, Braithwaite RS, Gao L, Byrne N, Walter D, Langford A. Dissemination of Misinformative and Biased Information about Prostate Cancer on YouTube. Eur Urol. 2018 Nov 27. pii: S0302-2838(18)30854-6.
- Prochaska M, Taylor EN, Curhan G. Menopause and Risk of Kidney Stones. J Urol. 2018 Oct;200(4):823-828.
- Hooton TM, Vecchio M, Iroz A, Tack I, Dornic Q, Seksek I, Lotan Y. Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract Infections: A Randomized Clinical Trial. JAMA Intern Med. 2018 Nov 1;178(11):1509-1515.
- Nassan FL, Chavarro JE, Tanrikut C. Diet and men's fertility: does diet affect sperm quality? Fertil Steril. 2018 Sep;110(4):570-577.